Sidney High School is a comprehensive college-prep-oriented public high school. The school year is divided into two semesters with four 9 week grading periods. The school day runs from 7:25 AM to 2:50 PM. Vocational students have the opportunity to attend the Upper Valley Career Center (UVCC) for vocational programs with several vocational programs also housed at SHS. Sidney High School is State accredited in Ohio by the Ohio Department of Education and is a member of the Miami Valley League and Ohio High School Athletic Association in athletics. All boys and girls sports are Division 1 with the exception of football, which is Division 2.

Sidney High School has 55 professionally trained certified staff members plus an additional 5 certified teachers who teach UVCC satellite vocational programs. Approximately 66% of the teaching staff have master's degrees with over half of these having additional post-graduate work beyond the master's level.

Sidney High School's average enrollment is 980, with around 100 students attending the Upper Valley Career Center. The average graduating class size is approximately 250 students.

Students at Sidney High School have access to approximately 15 College Credit Plus (college-level) and Advanced Placement courses offered on campus. Additionally, students may take classes at Edison State Community College. 

Sidney City Schools offers more than 70 extracurricular activities for students from 6th grade on. Sports include football; boys & girls soccer; boys & girls basketball; boys baseball; girls fastpitch; boys & girls tennis; co-ed track; co-ed bowling; boys & girls swimming; co-ed cross country; girls volleyball; boys wrestling; weightlifting; cheerleading; marching band; and golf. Clubs include Academia, Art Club, Breakfast Club, Business Professionals of America, Chess Club, Drama Club, FCCLA, Foreign Language Club, FFA, Key Club, Mock Trial, National Honor Society, Student Government, and others.